SEED Subsystem: DNA-replication in Escherichia coli BW25113

Experiments:

Role Gene Name Nalidixic 0.0313 mM  
⨯
ATP-dependent DNA helicase RecG (EC 3.6.1.-) b3652 recG -1.3
ATP-dependent DNA helicase RecQ b3822 recQ +0.0
Arrested fork binding No genes
Chromosomal replication initiator protein DnaA b2496 hda N.D.
  b3702 dnaA N.D.
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) b1863 ruvC -1.4
DNA polymerase I (EC 2.7.7.7) b2798 ygdG -0.0
  b3863 polA +0.1
DNA polymerase II (EC 2.7.7.7) b0060 polB +0.0
DNA polymerase III alpha subunit (EC 2.7.7.7) b0184 dnaE N.D.
DNA polymerase III beta subunit (EC 2.7.7.7) b3701 dnaN N.D.
DNA polymerase III chi subunit (EC 2.7.7.7) b4259 holC N.D.
DNA polymerase III delta prime subunit (EC 2.7.7.7) b1099 holB N.D.
DNA polymerase III delta subunit (EC 2.7.7.7) b0640 holA N.D.
DNA polymerase III epsilon subunit (EC 2.7.7.7) b0215 dnaQ N.D.
DNA polymerase III psi subunit (EC 2.7.7.7) b4372 holD N.D.
DNA polymerase III subunits gamma and tau (EC 2.7.7.7) b0470 dnaX N.D.
DNA polymerase III theta subunit (EC 2.7.7.7) b1842 holE +0.0
DNA primase (EC 2.7.7.-) b3066 dnaG N.D.
DNA primase (EC 2.7.7.-), phage-associated No genes
DNA primase TraC (EC 2.7.7.-) No genes
DNA repair protein RecN b2616 recN -3.3
DNA replication protein DnaC b4361 dnaC N.D.
DNA replication terminus site-binding protein b1610 tus +1.0
Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) b2819 recD -0.6
Exodeoxyribonuclease V beta chain (EC 3.1.11.5) b2820 recB -0.1
Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) b2822 recC -0.7
Helicase PriA essential for oriC/DnaA-independent DNA replication b3935 priA -3.4
Helicase loader DnaI No genes
Holliday junction DNA helicase RuvA b1861 ruvA -1.7
Holliday junction DNA helicase RuvB b1860 ruvB -0.3
Primosomal protein I b4362 dnaT N.D.
Primosomal replication protein N b4201 priB -3.6
Primosomal replication protein N prime prime b0467 priC -0.4
RecA protein b2699 recA -0.3
Recombination protein RecR b0472 recR -0.3
Replicative DNA helicase (EC 3.6.1.-) b4052 dnaB N.D.
Replicative DNA helicase (EC 3.6.1.-) [SA14-24] No genes
Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) b2892 recJ -0.7
Transcription-repair coupling factor b1114 mfd -0.2

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