MetaCyc Pathway: superpathway of L-threonine biosynthesis in Pseudomonas fluorescens GW456-L13

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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
PfGW456L13_2059
PfGW456L13_2142
PfGW456L13_2252
PfGW456L13_2943
PfGW456L13_2947
PfGW456L13_3163
PfGW456L13_3206
PfGW456L13_3261
PfGW456L13_3292
PfGW456L13_3363
PfGW456L13_4175
PfGW456L13_4396
PfGW456L13_4856
PfGW456L13_4919
PfGW456L13_4930
PfGW456L13_733
PfGW456L13_807
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
PfGW456L13_1981
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
PfGW456L13_3943
PfGW456L13_3944
PfGW456L13_4598
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3)
PfGW456L13_1723
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+ (EC 2.7.1.39)
PfGW456L13_3746
PfGW456L13_4124
PfGW456L13_596
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate (EC 4.2.3.1)
PfGW456L13_1724

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information