MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Pseudomonas fluorescens GW456-L13

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glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)
PfGW456L13_1761
PfGW456L13_2105
PfGW456L13_2119
PfGW456L13_2345
PfGW456L13_2496
PfGW456L13_252
PfGW456L13_2520
PfGW456L13_2522
PfGW456L13_30
PfGW456L13_3401
PfGW456L13_3418
PfGW456L13_3421
PfGW456L13_3426
PfGW456L13_3433
PfGW456L13_3458
PfGW456L13_3461
PfGW456L13_3464
PfGW456L13_3610
PfGW456L13_3752
PfGW456L13_388
PfGW456L13_4129
PfGW456L13_437
PfGW456L13_4657
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)
PfGW456L13_2041
PfGW456L13_4697
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)
PfGW456L13_2534
PfGW456L13_2912
PfGW456L13_3347
PfGW456L13_3413
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
PfGW456L13_1148

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information