MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Pseudomonas fluorescens GW456-L13

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
PfGW456L13_2059
PfGW456L13_2142
PfGW456L13_2177
PfGW456L13_2252
PfGW456L13_2943
PfGW456L13_2947
PfGW456L13_3163
PfGW456L13_3206
PfGW456L13_3261
PfGW456L13_3292
PfGW456L13_3363
PfGW456L13_3960
PfGW456L13_4175
PfGW456L13_4396
PfGW456L13_4856
PfGW456L13_4919
PfGW456L13_4930
PfGW456L13_4999
PfGW456L13_733
PfGW456L13_807
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA
(EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information