MetaCyc Pathway: gondoate biosynthesis (anaerobic) in Pseudomonas fluorescens GW456-L13

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
an oleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxo-icos-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
PfGW456L13_2040
PfGW456L13_2107
PfGW456L13_2194
PfGW456L13_250
PfGW456L13_253
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxo-icos-11-enoyl-[acp][cytosol] + NADPH[cytosol] + H+[cytosol]→a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol] + NADP+[cytosol] (EC 1.1.1.100)
PfGW456L13_1761
PfGW456L13_2105
PfGW456L13_2119
PfGW456L13_2345
PfGW456L13_2496
PfGW456L13_252
PfGW456L13_2520
PfGW456L13_2522
PfGW456L13_30
PfGW456L13_3401
PfGW456L13_3418
PfGW456L13_3421
PfGW456L13_3426
PfGW456L13_3433
PfGW456L13_3458
PfGW456L13_3461
PfGW456L13_3464
PfGW456L13_3610
PfGW456L13_3752
PfGW456L13_388
PfGW456L13_4129
PfGW456L13_437
PfGW456L13_4657
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol]→a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + H2O[cytosol] (EC 4.2.1.59)
PfGW456L13_2041
PfGW456L13_4697
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + NADH[cytosol] + H+[cytosol]→a gondoyl-[acp][cytosol] + NAD+[cytosol] (EC 1.3.1.9)
PfGW456L13_2534
PfGW456L13_2912
PfGW456L13_3347
PfGW456L13_3413

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information