| 9-cis, 11-trans-octadecadienoyl-CoA + 2 coenzyme A + 2 NAD+ + 2 dioxygen + 2 H2O→5-cis, 7-trans-tetradecadienoyl-CoA + 2 acetyl-CoA + 2 hydrogen peroxide + 2 NADH + 2 H+ |
| No genes |
Acyl-CoA oxidase:
5-cis, 7-trans-tetradecadienoyl-CoA + dioxygen→2-trans, 5-cis, 7-trans-tetradecatrienoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
| 2-trans, 5-cis, 7-trans-tetradecatrienoyl-CoA + H2O→(3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA (EC 4.2.1.119) |
| No genes |
| (3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA + NAD+→5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA + NADH + H+ (EC 1.1.1.M19) |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA + coenzyme A→(3Z,5E)-dodec-3,5-dienoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| PfGW456L13_2157 |
| PfGW456L13_2411 |
| PfGW456L13_2430 |
| PfGW456L13_2498 |
| PfGW456L13_2538 |
| PfGW456L13_2539 |
| PfGW456L13_29 |
| PfGW456L13_2982 |
| PfGW456L13_3394 |
| PfGW456L13_3408 |
| PfGW456L13_4040 |
| PfGW456L13_4147 |
| PfGW456L13_4590 |
Dodecenoyl-CoA isomerase:
(3Z,5E)-dodec-3,5-dienoyl-CoA→(2E,5E)-dodeca-2,5-dienoyl-CoA (EC 5.3.3.8) |
| PfGW456L13_4041 |
| PfGW456L13_412 |
| (2E,5E)-dodeca-2,5-dienoyl-CoA + H2O→(3R)-hydroxy-5-trans-dodecenoyl-CoA (EC 4.2.1.119) |
| No genes |
| (3R)-hydroxy-5-trans-dodecenoyl-CoA + NAD+→(5E)-3-oxo-dodec-5-enoyl-CoA + NADH + H+ (EC 1.1.1.M19) |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(5E)-3-oxo-dodec-5-enoyl-CoA + coenzyme A→(3E)-dec-3-enoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| PfGW456L13_2157 |
| PfGW456L13_2411 |
| PfGW456L13_2430 |
| PfGW456L13_2498 |
| PfGW456L13_2538 |
| PfGW456L13_2539 |
| PfGW456L13_29 |
| PfGW456L13_2982 |
| PfGW456L13_3394 |
| PfGW456L13_3408 |
| PfGW456L13_4040 |
| PfGW456L13_4147 |
| PfGW456L13_4590 |
Dodecenoyl-CoA isomerase:
(3E)-dec-3-enoyl-CoA→(2E)-dec-2-enoyl-CoA (EC 5.3.3.8) |
| PfGW456L13_4041 |
| PfGW456L13_412 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information