MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Pseudomonas fluorescens GW456-L13

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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
PfGW456L13_4785
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
PfGW456L13_271
PfGW456L13_3507
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
PfGW456L13_1217
PfGW456L13_1220
PfGW456L13_1310
PfGW456L13_1714
PfGW456L13_1784
PfGW456L13_1947
PfGW456L13_2154
PfGW456L13_2223
PfGW456L13_2547
PfGW456L13_271
PfGW456L13_272
PfGW456L13_3117
PfGW456L13_3507
PfGW456L13_3622
PfGW456L13_3652
PfGW456L13_3742
PfGW456L13_3914
PfGW456L13_4123
PfGW456L13_4145
PfGW456L13_4227
PfGW456L13_4364
PfGW456L13_4595
PfGW456L13_4688
PfGW456L13_4785
PfGW456L13_4817
PfGW456L13_5034
PfGW456L13_5035
PfGW456L13_5036
PfGW456L13_5099
PfGW456L13_5100
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
PfGW456L13_1993
PfGW456L13_2714
PfGW456L13_3221
PfGW456L13_342
PfGW456L13_3804
PfGW456L13_4498
PfGW456L13_925
PfGW456L13_926
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
PfGW456L13_1455
PfGW456L13_271
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
PfGW456L13_1310
PfGW456L13_1714
PfGW456L13_1784
PfGW456L13_2223
PfGW456L13_2547
PfGW456L13_271
PfGW456L13_272
PfGW456L13_3507
PfGW456L13_3742
PfGW456L13_4227
PfGW456L13_4364
PfGW456L13_4595

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information