MetaCyc Pathway: methylglyoxal degradation I in Pseudomonas fluorescens GW456-L13

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Lactoylglutathione lyase (in reverse):
methylglyoxal + glutathione→(R)-S-lactoylglutathione
(EC 4.4.1.5)
PfGW456L13_2380
PfGW456L13_2929
Hydroxyacylglutathione hydrolase:
(R)-S-lactoylglutathione + H2O→(R)-lactate + glutathione + H+
(EC 3.1.2.6)
PfGW456L13_3340
PfGW456L13_4681
(R)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.12)
PfGW456L13_5118

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information