MetaCyc Pathway: trans-4-hydroxy-L-proline degradation I in Pseudomonas fluorescens GW456-L13

Add experiment(s):


trans-4-hydroxy-L-proline[in] + an electron-transfer quinone→(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate[in] + an electron-transfer quinol + H+[in] (EC 1.5.5.3)
No genes
(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + H+ + H2O→L-4-hydroxyglutamate semialdehyde (spontaneous)
No genes
L-4-hydroxyglutamate semialdehyde + NAD+ + H2O→erythro-4-hydroxy-L-glutamate + NADH + 2 H+
No genes
4-hydroxyglutamate transaminase:
erythro-4-hydroxy-L-glutamate + 2-oxoglutarate→(4R)-4-hydroxy-2-oxoglutarate + L-glutamate (EC 2.6.1.23)
PfGW456L13_2059
PfGW456L13_2142
PfGW456L13_2252
PfGW456L13_2943
PfGW456L13_2947
PfGW456L13_3163
PfGW456L13_3206
PfGW456L13_3261
PfGW456L13_3292
PfGW456L13_3363
PfGW456L13_4175
PfGW456L13_4396
PfGW456L13_4856
PfGW456L13_4919
PfGW456L13_4930
PfGW456L13_733
PfGW456L13_807
4-hydroxy-2-oxoglutarate aldolase:
(4R)-4-hydroxy-2-oxoglutarate→glyoxylate + pyruvate (EC 4.1.3.16)
PfGW456L13_1903

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information