MetaCyc Pathway: pyruvate fermentation to acetone in Xanthobacter sp. DMC5

MetaCyc Pathway: pyruvate fermentation to acetone in Xanthobacter sp. DMC5

Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO₂ + H⁺ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)

No genes

Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)

Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA (EC 2.8.3.9)

Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA (EC 2.8.3.9)

Acetoacetate decarboxylase:
acetoacetate + H⁺→acetone + CO₂ (EC 4.1.1.4)

Links:

Pathway details at MetaCyc
Fitness data for 16 genes
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All MetaCyc pathways for Xanthobacter sp. DMC5

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information