MetaCyc Pathway: formaldehyde oxidation VI (H4MPT pathway) in Xanthobacter sp. DMC5

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formaldehyde + tetrahydromethanopterin→5,10-methylene-tetrahydromethanopterin + H2O (EC 4.2.1.147)
GFF2357
GFF3855
5,10-methylene-tetrahydromethanopterin + NAD(P)+→5,10-methenyltetrahydromethanopterin + NAD(P)H
GFF3696
Methenyltetrahydromethanopterin cyclohydrolase:
5,10-methenyltetrahydromethanopterin + H2O→5-formyl-tetrahydromethanopterin + H+ (EC 3.5.4.27)
GFF3697
5-formyl-tetrahydromethanopterin + H2O→formate + H+ + tetrahydromethanopterin
GFF3702
GFF3703

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information