MetaCyc Pathway: 3-phenylpropanoate degradation in Xanthobacter sp. DMC5

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3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
GFF1075
GFF1383
GFF1591
GFF184
GFF2006
GFF2039
GFF2391
GFF27
GFF2812
GFF2820
GFF2845
GFF3007
GFF3344
GFF4218
GFF4249
GFF4546
GFF4769
GFF4803
GFF494
GFF517
GFF704
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
GFF1284
GFF184
GFF2812
GFF3570
GFF4195
GFF517
GFF589
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
GFF1285
GFF1381
GFF1435
GFF183
GFF2377
GFF33
GFF4330
GFF4817
GFF518
GFF606
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
No genes
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
GFF4529
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
GFF4568

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information