MetaCyc Pathway: superpathway of 2,3-butanediol biosynthesis in Pseudomonas simiae WCS417

MetaCyc Pathway: superpathway of 2,3-butanediol biosynthesis in Pseudomonas simiae WCS417

Acetolactate synthase:
2 pyruvate + H⁺→(S)-2-acetolactate + CO₂ (EC 2.2.1.6)

(R)-acetoin + NADH + H⁺→(R,S)-2,3-butanediol + NAD⁺

(S)-2-acetolactate + an oxidized electron carrier + H⁺→CO₂ + diacetyl + a reduced two electron carrier (spontaneous)

No genes

diacetyl + NADH + H⁺→(S)-acetoin + NAD⁺ (EC 1.1.1.304)

(S)-acetoin + NADH + H⁺→(R,S)-2,3-butanediol + NAD⁺

No genes

(S,S)-butanediol dehydrogenase (in reverse):
(S)-acetoin + NADH + H⁺→(S,S)-2,3-butanediol + NAD⁺ (EC 1.1.1.76)

Links:

Pathway details at MetaCyc
Fitness data for 7 genes
Select organism:
All MetaCyc pathways for Pseudomonas simiae WCS417

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information