MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Pseudomonas simiae WCS417

Phosphoenolpyruvate carboxylase (in reverse): phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)

PS417_06060

Citrate (Si)-synthase: oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)

PS417_08870

oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)

PS417_07955

PS417_04460

Aconitate hydratase: citrate→cis-aconitate + H2O (EC 4.2.1.3)

PS417_07515

PS417_14990

PS417_21070

Fumarate hydratase: (S)-malate→fumarate + H2O (EC 4.2.1.2)

PS417_11625

PS417_19200

PS417_22635

PS417_04305

Aconitate hydratase: cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)

PS417_07515

PS417_14990

PS417_21070

Succinate dehydrogenase (ubiquinone) (in reverse): fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)

PS417_08875

PS417_08880

PS417_08885

PS417_08890

Isocitrate dehydrogenase (NADP(+)): D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)

PS417_16525

PS417_16530

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information