Phospholipase A(2):
a [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H2O→(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + a glycerolipid + H+ (EC 3.1.1.4) |
| No genes |
Arachidonate 15-lipoxygenase:
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + dioxygen→(17S)-HpDHA (EC 1.13.11.33) |
| GFF5228 |
Phospholipid-hydroperoxide glutathione peroxidase:
(17S)-HpDHA + 2 glutathione→17(S)-HDoHE + glutathione disulfide + H2O (EC 1.11.1.12) |
| No genes |
Arachidonate 5-lipoxygenase:
17(S)-HDoHE + dioxygen→(7S,17S)-17-hydroxy-7-hydroperoxydocosahexaenoate (EC 1.13.11.34) |
| No genes |
Arachidonate 5-lipoxygenase:
17(S)-HDoHE + dioxygen→(4S,17S)-17-hydroxy-4-hydroperoxydocosahexaenoate (EC 1.13.11.34) |
| No genes |
Arachidonate 5-lipoxygenase:
(4S,17S)-17-hydroxy-4-hydroperoxydocosahexaenoate→4(5)-epoxy-17S-hydroxy-docosahexaenoate + H2O (EC 1.13.11.34) |
| No genes |
Arachidonate 5-lipoxygenase:
(7S,17S)-17-hydroxy-7-hydroperoxydocosahexaenoate→(7S,8S)-epoxy-resolvin + H2O (EC 1.13.11.34) |
| No genes |
| (7S,8S)-epoxy-resolvin + H2O→resolvin D1 |
| No genes |
| (7S,8S)-epoxy-resolvin + H2O→resolvin D2 |
| No genes |
| 4(5)-epoxy-17S-hydroxy-docosahexaenoate + H2O→resolvin D3 |
| No genes |
| 4(5)-epoxy-17S-hydroxy-docosahexaenoate + H2O→resolvin D4 |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information