Arachidonate 15-lipoxygenase:
arachidonate + dioxygen→(15S)-HpETE (EC 1.13.11.33) |
| GFF5228 |
Arachidonate 5-lipoxygenase:
arachidonate + dioxygen→(5S)-HpETE (EC 1.13.11.34) |
| No genes |
Arachidonate 5-lipoxygenase:
(5S)-HpETE→leukotriene A4 + H2O (EC 1.13.11.34) |
| No genes |
Phospholipid-hydroperoxide glutathione peroxidase:
(15S)-HpETE + 2 glutathione→15(S)-HETE + glutathione disulfide + H2O (EC 1.11.1.12) |
| No genes |
Arachidonate 12-lipoxygenase:
leukotriene A4 + a reduced two electron carrier + dioxygen→(5S,7E,9E,11Z,13E,15S)-15-hydroperoxy-5-hydroxyicosa-7,9,11,13-tetraenoate + an oxidized electron carrier (EC 1.13.11.31) |
| No genes |
Arachidonate 15-lipoxygenase:
15(S)-HETE + dioxygen→(5S,6E,8Z,11Z,13E,15S)-5-hydroperoxy-15-hydroxyicosa-6,8,11,13-tetraenoate (EC 1.13.11.33; 1.13.11.34) |
| GFF5228 |
Arachidonate 15-lipoxygenase:
(5S,6E,8Z,11Z,13E,15S)-5-hydroperoxy-15-hydroxyicosa-6,8,11,13-tetraenoate→(7E,9E,11Z,13E,15S)-(5S,6S)-5,6-epoxyicosa-15-hydroxy-7,9,11,13-tetraenoate + H2O (EC 1.13.11.33; 1.13.11.34) |
| GFF5228 |
| (5S,7E,9E,11Z,13E,15S)-15-hydroperoxy-5-hydroxyicosa-7,9,11,13-tetraenoate→lipoxin A4 (spontaneous) |
| No genes |
| (5S,7E,9E,11Z,13E,15S)-15-hydroperoxy-5-hydroxyicosa-7,9,11,13-tetraenoate→lipoxin B4 (spontaneous) |
| No genes |
| (7E,9E,11Z,13E,15S)-(5S,6S)-5,6-epoxyicosa-15-hydroxy-7,9,11,13-tetraenoate + H2O→lipoxin A4 |
| No genes |
Arachidonate 15-lipoxygenase:
(7E,9E,11Z,13E,15S)-(5S,6S)-5,6-epoxyicosa-15-hydroxy-7,9,11,13-tetraenoate + H2O→lipoxin B4 (EC 1.13.11.33) |
| GFF5228 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information