MetaCyc Pathway: ketolysis in Variovorax sp. SCN45

MetaCyc Pathway: ketolysis in Variovorax sp. SCN45

3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD⁺→acetoacetate + NADH + H⁺ (EC 1.1.1.30)

3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate (EC 2.8.3.5)

Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)

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Pathway details at MetaCyc
Fitness data for 24 genes
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All MetaCyc pathways for Variovorax sp. SCN45

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information