MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Variovorax sp. SCN45

Add experiment(s):


propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
GFF1040
GFF1065
GFF1348
GFF1568
GFF1573
GFF2104
GFF2166
GFF2281
GFF2420
GFF2421
GFF2643
GFF2697
GFF2922
GFF2967
GFF3062
GFF308
GFF3448
GFF3859
GFF3976
GFF3986
GFF4204
GFF4278
GFF4286
GFF4298
GFF4314
GFF4319
GFF4357
GFF4358
GFF4616
GFF4866
GFF4965
GFF4969
GFF4970
GFF4976
GFF5584
GFF6068
GFF6541
GFF6804
GFF6902
GFF7056
GFF7089
GFF7388
GFF84
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
GFF382
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information