Phospholipase A(2):
a [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H2O→(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + a glycerolipid + H+ (EC 3.1.1.4) |
| No genes |
Arachidonate 15-lipoxygenase:
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + dioxygen→(17S)-HpDHA (EC 1.13.11.33) |
| GFF5228 |
Arachidonate 15-lipoxygenase:
(17S)-HpDHA→(16S,17S)-epoxy-protectin + H2O (EC 1.13.11.33) |
| GFF5228 |
Arachidonate 15-lipoxygenase:
(17S)-HpDHA + dioxygen→(10S,17S)-diHpDHA (EC 1.13.11.33) |
| GFF5228 |
| (16S,17S)-epoxy-protectin + H2O→protectin D1 |
| No genes |
Phospholipid-hydroperoxide glutathione peroxidase:
(10S,17S)-diHpDHA + 4 glutathione→protectin DX + 2 glutathione disulfide + 2 H2O (EC 1.11.1.12) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information