MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Variovorax sp. SCN45

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
GFF1574
GFF1934
GFF2336
GFF2409
GFF245
GFF2454
GFF2803
GFF3057
GFF3375
GFF3955
GFF4109
GFF4125
GFF417
GFF4743
GFF5025
GFF5154
GFF5348
GFF573
GFF5904
GFF621
GFF6304
GFF6644
GFF6886
GFF7014
GFF7134
GFF7679
GFF7682
GFF7897
GFF844
GFF944
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information