MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Variovorax sp. SCN45

Add experiment(s):


Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
GFF6424
GFF7706
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
GFF5504
GFF6584
GFF7468
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
GFF6424
GFF7706
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
GFF2803
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
GFF1718
GFF3901
GFF414
GFF4621
GFF7263
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
GFF1749
GFF5109
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
GFF1574
GFF1934
GFF2336
GFF2409
GFF245
GFF2454
GFF2803
GFF3057
GFF3375
GFF4109
GFF4125
GFF4743
GFF5025
GFF5154
GFF573
GFF5904
GFF621
GFF6644
GFF6886
GFF7014
GFF7134
GFF7679
GFF7682
GFF7897
GFF844
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
GFF1583
GFF1584
GFF1887
GFF479
GFF483
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
GFF5586
GFF5587
GFF7746
GFF968
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
GFF931
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
GFF5405
GFF5406
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
GFF938
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
GFF3881
GFF548
GFF934
GFF936

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information