MetaCyc Pathway: anaerobic energy metabolism (invertebrates, cytosol) in Variovorax sp. SCN45

MetaCyc Pathway: anaerobic energy metabolism (invertebrates, cytosol) in Variovorax sp. SCN45

Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO₂ + GDP→oxaloacetate + GTP (EC 4.1.1.32)

Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H⁺→pyruvate + ATP (EC 2.7.1.40)

Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO₂ + IDP→oxaloacetate + ITP (EC 4.1.1.32)

Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)

Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)

Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)

Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H⁺→(S)-malate + NAD⁺ (EC 1.1.1.37; 1.1.1.38)

Links:

Pathway details at MetaCyc
Fitness data for 37 genes
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All MetaCyc pathways for Variovorax sp. SCN45

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information