MetaCyc Pathway: methylglyoxal degradation V in Variovorax sp. SCN45

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Methylglyoxal reductase (NADPH-dependent) (in reverse):
methylglyoxal + NADPH + H+→(S)-lactaldehyde + NADP+
(EC 1.1.1.283)
GFF7348
GFF7528
Lactaldehyde dehydrogenase:
(S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+
(EC 1.2.1.22)
GFF2364
GFF4162
GFF5027
L-lactate dehydrogenase (cytochrome):
(S)-lactate + 2 an oxidized c-type cytochrome→pyruvate + 2 a reduced c-type cytochrome + 2 H+
(EC 1.1.2.3)
GFF1422
GFF1833
GFF5984

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information