MetaCyc Pathway: β-alanine biosynthesis II in Variovorax sp. SCN45

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Propionate--CoA ligase:
propanoate + ATP + coenzyme A→propanoyl-CoA + AMP + diphosphate
(EC 6.2.1.17)
GFF475
GFF6925
GFF978
propanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→acryloyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.1)
GFF1345
acryloyl-CoA + H2O→3-hydroxypropanoyl-CoA (EC 4.2.1.116)
No genes
3-hydroxyisobutyryl-CoA hydrolase:
3-hydroxypropanoyl-CoA + H2O→3-hydroxypropanoate + coenzyme A + H+
(EC 3.1.2.4)
GFF7380
3-hydroxypropionate dehydrogenase:
3-hydroxypropanoate + NAD+→3-oxopropanoate + NADH + H+
(EC 1.1.1.59)
GFF5040
Beta-alanine--pyruvate transaminase:
3-oxopropanoate + L-alanine→β-alanine + pyruvate
(EC 2.6.1.18)
GFF3791
GFF6150
GFF918

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information