MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Variovorax sp. SCN45

MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Variovorax sp. SCN45

Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)

Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate (EC 4.3.1.1)

Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H⁺ (EC 6.3.1.1)

No genes

Asparaginase:
L-asparagine + H₂O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4)

Links:

Pathway details at MetaCyc
Fitness data for 29 genes
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All MetaCyc pathways for Variovorax sp. SCN45

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information