MetaCyc Pathway: L-phenylalanine degradation VI (reductive Stickland reaction) in Variovorax sp. OAS795

Add experiment(s):


Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
ABID97_RS04080
ABID97_RS05635
ABID97_RS06550
ABID97_RS08770
ABID97_RS10885
ABID97_RS13335
ABID97_RS13990
ABID97_RS16605
ABID97_RS17310
ABID97_RS17960
ABID97_RS18035
ABID97_RS20530
ABID97_RS21960
ABID97_RS23145
ABID97_RS24840
ABID97_RS27360
ABID97_RS27595
ABID97_RS27655
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(phenyl)lactate + (E)-cinnamoyl-CoA→(R)-3-(phenyl)lactoyl-CoA + trans-cinnamate
(EC 2.8.3.17)
No genes
trans-cinnamate + a reduced electron-transfer flavoprotein→3-phenylpropanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(phenyl)lactoyl-CoA→(E)-cinnamoyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information