MetaCyc Pathway: IM-2 type γ-butyrolactones biosynthesis in Variovorax sp. OAS795

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glycerone phosphate + a medium-chain 3-oxoacyl-[acp]→a 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate + a soluble holo-[acyl-carrier protein] (EC 2.3.1.277)
No genes
a 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate→a (4-alkanoyl-5-oxo-2H-furan-3-yl)methyl phosphate + H2O (spontaneous)
No genes
a (4-alkanoyl-5-oxo-2H-furan-3-yl)methyl phosphate + NADPH + H+→a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP+ (EC 1.3.1.113)
No genes
a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate + H2O→an A-factor type γ-butyrolactone + phosphate
No genes
an A-factor type γ-butyrolactone + NADPH + H+→an IM-2 type γ-butyrolactone + NADP+ (EC 1.1.1.eb)
ABID97_RS01400

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information