MetaCyc Pathway: crotonate fermentation (to acetate and cyclohexane carboxylate) in Variovorax sp. OAS795

Add experiment(s):


acetyl-CoA + crotonate→acetate + crotonyl-CoA
No genes
crotonyl-CoA + CO2→(E)-glutaconyl-CoA + H+ (EC 1.3.8.6)
No genes
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150)
ABID97_RS00815
ABID97_RS01435
ABID97_RS02880
ABID97_RS04670
ABID97_RS05865
ABID97_RS05900
ABID97_RS05990
ABID97_RS06010
ABID97_RS07755
ABID97_RS10620
ABID97_RS15740
ABID97_RS17010
ABID97_RS17470
ABID97_RS18490
ABID97_RS18600
ABID97_RS18605
ABID97_RS18635
ABID97_RS20990
ABID97_RS22770
ABID97_RS24015
ABID97_RS24805
ABID97_RS26735
ABID97_RS27490
ABID97_RS27535
ABID97_RS27555
ABID97_RS27620
ABID97_RS28260
ABID97_RS28410
ABID97_RS29050
(E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein→glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.6)
No genes
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
ABID97_RS00810
ABID97_RS03030
ABID97_RS05865
ABID97_RS06010
ABID97_RS08805
ABID97_RS10560
ABID97_RS15740
ABID97_RS17005
ABID97_RS18595
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
ABID97_RS04675
ABID97_RS05875
ABID97_RS06005
ABID97_RS10975
ABID97_RS11335
ABID97_RS11380
ABID97_RS12420
ABID97_RS15750
ABID97_RS18615
ABID97_RS18775
ABID97_RS20240
ABID97_RS24190
ABID97_RS25195
ABID97_RS26575
ABID97_RS27835
ABID97_RS28230
ABID97_RS28270
ABID97_RS28430
acetyl-CoA + glutaryl-CoA→3-oxopimeloyl-CoA + coenzyme A
ABID97_RS05875
ABID97_RS15750
ABID97_RS27835
3-hydroxypimeloyl-CoA dehydrogenase (in reverse):
3-oxopimeloyl-CoA + NADH + H+→3-hydroxypimeloyl-CoA + NAD+ (EC 1.1.1.259)
No genes
Acetate--CoA ligase (ADP-forming) (in reverse):
acetyl-CoA + ADP + phosphate→acetate + ATP + coenzyme A (EC 6.2.1.13)
No genes
3-hydroxypimeloyl-CoA + H+→2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O (EC 3.7.1.21)
No genes
2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA→6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O (EC 3.7.1.21)
No genes
6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+→6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ (EC 1.1.1.368)
No genes
Cyclohexa-1,5-dienecarbonyl-CoA hydratase:
6-hydroxycyclohex-1-ene-1-carbonyl-CoA→cyclohex-1,5-diene-1-carbonyl-CoA + H2O (EC 4.2.1.100)
No genes
cyclohex-1,5-diene-1-carbonyl-CoA + a reduced electron-transfer flavoprotein→cyclohex-1-ene-1-carbonyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.10)
No genes
cyclohex-1-ene-1-carbonyl-CoA + a reduced electron-transfer flavoprotein→cyclohexane-1-carbonyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.11)
No genes
cyclohexane-1-carbonyl-CoA + H2O→cyclohexane-1-carboxylate + coenzyme A + H+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information