MetaCyc Pathway: 4-hydroxy-2-nonenal detoxification in Variovorax sp. OAS795

Add experiment(s):


Glutathione transferase:
4-hydroxy-2-nonenal + glutathione→(glutathion-S-yl)-4-hydroxy-2-nonenal (EC 2.5.1.18)
ABID97_RS00290
ABID97_RS00905
ABID97_RS02045
ABID97_RS02885
ABID97_RS06585
ABID97_RS10130
ABID97_RS10240
ABID97_RS10440
ABID97_RS12400
ABID97_RS14430
ABID97_RS14560
ABID97_RS15785
ABID97_RS19305
ABID97_RS21270
ABID97_RS21420
ABID97_RS24745
ABID97_RS27350
ABID97_RS27770
(glutathion-S-yl)-4-hydroxy-2-nonenal + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + L-glutamate (EC 3.4.19.13)
No genes
S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteine + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
S-(4-hydroxy-nonenal-3-yl)-L-cysteine + acetyl-CoA→4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ (EC 2.3.1.80)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information