MetaCyc Pathway: isopropanol biosynthesis (engineered) in Variovorax sp. OAS795

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Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
ABID97_RS04675
ABID97_RS05875
ABID97_RS06005
ABID97_RS10975
ABID97_RS11335
ABID97_RS11380
ABID97_RS12420
ABID97_RS15750
ABID97_RS18615
ABID97_RS18775
ABID97_RS20240
ABID97_RS24190
ABID97_RS25195
ABID97_RS26575
ABID97_RS27835
ABID97_RS28230
ABID97_RS28270
ABID97_RS28430
Acetoacetyl-CoA hydrolase:
acetoacetyl-CoA + H2O→acetoacetate + coenzyme A + H+ (EC 3.1.2.11)
No genes
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
No genes
Isopropanol dehydrogenase (NADP(+)) (in reverse):
acetone + NADPH + H+→propan-2-ol + NADP+ (EC 1.1.1.80)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information