MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Variovorax sp. OAS795

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
ABID97_RS28960
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
ABID97_RS00815
ABID97_RS01435
ABID97_RS02880
ABID97_RS03115
ABID97_RS04670
ABID97_RS05865
ABID97_RS05900
ABID97_RS05990
ABID97_RS06010
ABID97_RS07755
ABID97_RS10620
ABID97_RS14445
ABID97_RS15740
ABID97_RS17005
ABID97_RS17010
ABID97_RS17470
ABID97_RS18490
ABID97_RS18595
ABID97_RS18600
ABID97_RS18605
ABID97_RS18635
ABID97_RS19410
ABID97_RS20990
ABID97_RS22770
ABID97_RS24015
ABID97_RS24805
ABID97_RS26735
ABID97_RS27490
ABID97_RS27535
ABID97_RS27555
ABID97_RS27620
ABID97_RS28260
ABID97_RS28410
ABID97_RS29050
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information