MetaCyc Pathway: L-tyrosine degradation I in Ralstonia solanacearum UW163

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
UW163_RS00765
UW163_RS01295
UW163_RS03255
UW163_RS05655
UW163_RS06775
UW163_RS10995
UW163_RS11685
UW163_RS13315
UW163_RS15695
UW163_RS16045
UW163_RS19235
UW163_RS20415
UW163_RS21205
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
UW163_RS05940
UW163_RS18335
UW163_RS21715
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
UW163_RS18935
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
UW163_RS02530
UW163_RS12080
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
UW163_RS02535
UW163_RS12085
UW163_RS18930

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information