MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Pseudomonas putida KT2440

Add experiment(s):


Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+
(EC 1.1.1.95)
PP_0762
PP_2533
PP_3225
PP_4316
PP_4589
PP_5155
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamateO-phospho-L-serine + 2-oxoglutarate
(EC 2.6.1.52)
PP_1768
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate
(EC 3.1.3.3)
PP_1721
PP_4909
PP_5130
PP_5147
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O
(EC 2.1.2.1)
PP_0322
PP_0671
PP_0672

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information