MetaCyc Pathway: gluconeogenesis III in Pseudomonas putida KT2440

Add experiment(s):


Pyruvate carboxylase:
pyruvate + ATP + hydrogen carbonate→oxaloacetate + ADP + H+ + phosphate
(EC 6.4.1.1)
PP_5346
PP_5347
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
PP_0654
PP_2835
Phosphoenolpyruvate carboxykinase (GTP):
oxaloacetate + GTP→phosphoenolpyruvate + CO2 + GDP
(EC 4.1.1.32)
No genes
Phosphopyruvate hydratase (in reverse):
phosphoenolpyruvate + H2O→2-phospho-D-glycerate
(EC 4.2.1.11)
PP_1612
2-phospho-D-glycerate→3-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphoglycerate kinase:
3-phospho-D-glycerate + ATP→3-phospho-D-glyceroyl phosphate + ADP
(EC 2.7.2.3)
PP_4963
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (in reverse):
3-phospho-D-glyceroyl phosphate + NADH + H+→D-glyceraldehyde 3-phosphate + NAD+ + phosphate
(EC 1.2.1.12)
PP_1009
PP_2149
Triose-phosphate isomerase:
D-glyceraldehyde 3-phosphate→glycerone phosphate
(EC 5.3.1.1)
PP_4715
Fructose-bisphosphate aldolase (in reverse):
glycerone phosphate + D-glyceraldehyde 3-phosphate→β-D-fructofuranose 1,6-bisphosphate
(EC 4.1.2.13)
PP_4960
PP_4961
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate
(EC 3.1.3.11)
PP_5040
Glucose-6-phosphate isomerase (in reverse):
β-D-fructofuranose 6-phosphate→α-D-glucose 6-phosphate
(EC 5.3.1.9)
PP_1808
PP_4701
Sugar-terminal-phosphatase:
D-glucopyranose 6-phosphate + H2O→D-glucopyranose + phosphate
(EC 3.1.3.58; 3.1.3.9)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information