MetaCyc Pathway: glycine degradation in Pseudomonas putida KT2440

Add experiment(s):


glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27)
PP_5194
PP_5366
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate
(EC 2.1.2.1)
PP_0322
PP_0671
PP_0672
L-serine ammonia-lyase:
L-serine→ammonium + pyruvate
(EC 4.3.1.17)
PP_0297
PP_0987
PP_2930
PP_3144
PP_4430

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information