MetaCyc Pathway: pyruvate decarboxylation to acetyl CoA I in Pseudomonas sp. S08-1

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a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + NAD+→a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + NADH + H+ (EC 1.2.1.104; 1.8.1.4)
OH686_01960
OH686_23900
a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + pyruvate + H+→a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + CO2 (EC 1.2.1.104; 1.2.4.1)
OH686_09710
a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + coenzyme A→a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + acetyl-CoA (EC 1.2.1.104; 2.3.1.12)
OH686_09715

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information