MetaCyc Pathway: adipate degradation in Pseudomonas sp. S08-1

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Succinate--CoA ligase (ADP-forming):
adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate
(EC 6.2.1.5)
OH686_01950
OH686_01955
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
OH686_08875
OH686_09105
OH686_09785
OH686_10310
OH686_10320
OH686_17930
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA
(EC 4.2.1.17)
OH686_03545
OH686_05875
OH686_05880
OH686_09110
OH686_17935
OH686_18725
OH686_18795
OH686_21925
OH686_22350
OH686_22390
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+
(EC 1.1.1.35)
OH686_00865
OH686_05875
OH686_17935
OH686_21925
OH686_22350
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA
(EC 2.3.1.174)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information