MetaCyc Pathway: 2-methyl-branched fatty acid β-oxidation in Pseudomonas sp. S08-1

Add experiment(s):


Butyrate--CoA ligase:
a short-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.2)
No genes
a long-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a long-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.8)
OH686_08415
Butyrate--CoA ligase:
a medium-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.2)
No genes
a short-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a short-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.5)
No genes
a medium-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a medium-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
OH686_08415
OH686_08875
OH686_09105
OH686_09785
OH686_10310
OH686_10320
OH686_17930
Enoyl-CoA hydratase (in reverse):
a long-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a long-chain (3S)-3-hydroxy-2-methylacyl-CoA
(EC 4.2.1.17)
OH686_03545
OH686_05875
OH686_05880
OH686_09110
OH686_17935
OH686_18725
OH686_18795
OH686_21925
OH686_22350
OH686_22390
Enoyl-CoA hydratase (in reverse):
a short-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a short-chain (3S)-3-hydroxy-2-methylacyl-CoA
(EC 4.2.1.17)
OH686_03545
OH686_05875
OH686_05880
OH686_09110
OH686_17935
OH686_18725
OH686_18795
OH686_21925
OH686_22350
OH686_22390
Enoyl-CoA hydratase (in reverse):
a medium-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA
(EC 4.2.1.17)
OH686_03545
OH686_05875
OH686_05880
OH686_09110
OH686_17935
OH686_18725
OH686_18795
OH686_21925
OH686_22350
OH686_22390
3-hydroxyacyl-CoA dehydrogenase:
a long-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a long-chain 2-methyl-3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
OH686_00865
OH686_17935
OH686_21925
OH686_22350
3-hydroxy-2-methylbutyryl-CoA dehydrogenase:
a short-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a short-chain 2-methyl-3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.178)
No genes
3-hydroxyacyl-CoA dehydrogenase:
a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a medium-chain 2-methyl-3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
OH686_00865
OH686_17935
OH686_21925
OH686_22350
Acetyl-CoA C-acyltransferase (in reverse):
a long-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a long-chain 2-methyl fatty acyl-CoA + propanoyl-CoA
(EC 2.3.1.16)
OH686_00870
OH686_06330
OH686_17215
OH686_17910
OH686_21930
OH686_22345
OH686_23885
Acetyl-CoA C-acyltransferase (in reverse):
a short-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + propanoyl-CoA
(EC 2.3.1.16)
OH686_00870
OH686_06330
OH686_17215
OH686_17910
OH686_21930
OH686_22345
OH686_23885
Acetyl-CoA C-acyltransferase (in reverse):
a medium-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + propanoyl-CoA
(EC 2.3.1.16)
OH686_00870
OH686_06330
OH686_17215
OH686_17910
OH686_21930
OH686_22345
OH686_23885

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information