MetaCyc Pathway: superpathway of cardiolipin biosynthesis (bacteria) in Pseudomonas sp. RS175

Add experiment(s):


Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+→sn-glycerol 3-phosphate + NAD(P)+ (EC 1.1.1.94)
PFR28_03076
a fatty acyl-[acyl-carrier protein] + phosphate→an acyl phosphate + a soluble [acyl-carrier protein] (EC 2.3.1.274)
No genes
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.15)
PFR28_00382
PFR28_03012
PFR28_04074
an acyl phosphate + sn-glycerol 3-phosphate→a 2-lysophosphatidate + phosphate (EC 2.3.1.275)
No genes
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.51)
PFR28_00639
PFR28_02958
PFR28_03185
PFR28_03925
PFR28_04598
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate (EC 2.7.7.41)
PFR28_00401
PFR28_03926
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
PFR28_01412
PFR28_03921
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+ (EC 2.7.8.8)
PFR28_01877
PFR28_03696
a CDP-diacylglycerol + a phosphatidylglycerol→a cardiolipin + CMP + H+ (EC 2.7.8.41)
PFR28_00645
PFR28_03966
PFR28_04405
PFR28_04539
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
PFR28_03943
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2 (EC 4.1.1.65)
PFR28_05107
2 a phosphatidylglycerol→a cardiolipin + glycerol (EC 2.7.8.41)
PFR28_03966
a phosphatidylethanolamine + a phosphatidylglycerol→a cardiolipin + ethanolamine (EC 2.7.8.41)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information