MetaCyc Pathway: dapdiamides biosynthesis in Pseudomonas sp. RS175

Add experiment(s):


L-serine + ATPO-phospho-L-serine + ADP + H+ (EC 2.7.1.225)
No genes
O-phospho-L-serine + L-glutamateN-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate (EC 2.5.1.140)
No genes
N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O→L-2,3-diaminopropanoate + 2-oxoglutarate + NADH + H+ (EC 1.5.1.51)
No genes
L-2,3-diaminopropanoate + ATP + fumarateN-3-fumaroyl-L-2,3-diaminopropanoate + AMP + diphosphate + H+ (EC 6.3.2.46)
No genes
N-3-fumaroyl-L-2,3-diaminopropanoate + ATP + L-glutamine + H2ON-3-fumaramoyl-L-2,3-diaminopropanoate + AMP + L-glutamate + diphosphate + H+
No genes
N-3-fumaramoyl-L-2,3-diaminopropanoate + ATP + L-valine→dapdiamide A + ADP + H+ + phosphate (EC 6.3.2.47)
No genes
N-3-fumaramoyl-L-2,3-diaminopropanoate + ATP + L-isoleucine→dapdiamide B + ADP + H+ + phosphate (EC 6.3.2.47)
No genes
N-3-fumaramoyl-L-2,3-diaminopropanoate + ATP + L-leucine→dapdiamide C + ADP + H+ + phosphate (EC 6.3.2.47)
No genes
N-3-fumaramoyl-L-2,3-diaminopropanoate + ATP + H+N-3-fumaramoyl-(S)-2,3-diaminopropanoyl-adenylate + diphosphate
No genes
N-3-fumaramoyl-(S)-2,3-diaminopropanoyl-adenylate + a DdaD non-ribosomal peptide synthase→an N-3-fumaramoyl-(S)-2,3-diaminopropanoyl-[DdaD non-ribosomal peptide synthase] + AMP + H+
No genes
an N-3-fumaramoyl-(S)-2,3-diaminopropanoyl-[DdaD non-ribosomal peptide synthase] + 2-oxoglutarate + dioxygen→an N-3-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-[DdaD non-ribosomal peptide synthase] + CO2 + succinate (EC 1.14.11.M2)
PFR28_02084
PFR28_02086
an N-3-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-[DdaD non-ribosomal peptide synthase] + H2ON-3-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoate + a DdaD non-ribosomal peptide synthase + H+
No genes
N-3-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoate + ATP + L-valineN-(R,R)-3-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine + ADP + H+ + phosphate (EC 6.3.2.47)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information