MetaCyc Pathway: heme <i>b</i> biosynthesis III (from siroheme) in Pseudomonas sp. RS175

MetaCyc Pathway: heme b biosynthesis III (from siroheme) in Pseudomonas sp. RS175

siroheme + 2 H⁺→12,18-didecarboxysiroheme + 2 CO₂ (EC 4.1.1.111)

12,18-didecarboxysiroheme + 2 a reduced two electron carrier + 2 S-adenosyl-L-methionine→Fe-coproporphyrin III + 2 acetate + 2 an oxidized electron carrier + 2 5'-deoxyadenosine + 2 L-methionine + 2 H⁺

PFR28_02238

Fe-coproporphyrin III + 2 S-adenosyl-L-methionine→protoheme + 2 CO₂ + 2 5'-deoxyadenosine + 2 L-methionine (EC 1.3.98.6)

No genes

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Pathway details at MetaCyc
Fitness data for 3 genes
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All MetaCyc pathways for Pseudomonas sp. RS175

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information