MetaCyc Pathway: D-cycloserine biosynthesis in Pseudomonas sp. RS175

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L-arginine + 2-oxoglutarate + dioxygen→Nω-hydroxy-L-arginine + CO2 + succinate
No genes
Serine O-acetyltransferase:
L-serine + acetyl-CoA→O-acetyl-L-serine + coenzyme A (EC 2.3.1.30)
PFR28_00284
Nω-hydroxy-L-arginine + H2O→hydroxyurea + L-ornithine (EC 3.5.3.25)
No genes
O-acetyl-L-serine + hydroxyurea→O-ureido-L-serine + acetate + H+ (EC 2.6.99.3)
No genes
O-ureido-L-serine→O-ureido-D-serine (EC 5.1.1.19)
No genes
O-ureido-D-serine + ATP + H+ + H2O→D-cycloserine + ADP + ammonium + CO2 + phosphate (EC 6.3.3.5)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information