MetaCyc Pathway: alginate biosynthesis II (bacterial) in Pseudomonas sp. RS175

GDP-mannose 6-dehydrogenase:
GDP-α-D-mannose + 2 NAD⁺ + H₂O→GDP-α-D-mannuronate + 2 NADH + 3 H⁺ (EC 1.1.1.132)

PFR28_03555

an acetylated acetyl acceptor_[in]→an acetylated acetyl acceptor_[out]

PFR28_03563

Alginate synthase:
n GDP-α-D-mannuronate→mannuronan + n GDP + n H⁺ (EC 2.4.1.33)

PFR28_03556

PFR28_03557

mannuronan_[in]→mannuronan_[out]

PFR28_03560

mannuronan→alginate (EC 5.1.3.37)

PFR28_03560

alginate + n an acetylated acetyl acceptor→acetylated alginate + n a non-acetylated acetyl acceptor

PFR28_03564

PFR28_03565

acetylated alginate_[in]→acetylated alginate_[out]

No genes

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Pathway details at MetaCyc
Fitness data for 7 genes
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All MetaCyc pathways for Pseudomonas sp. RS175

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information