MetaCyc Pathway: TCA cycle II (plants and fungi) in Pseudomonas sp. RS175

Add experiment(s):


2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
PFR28_03092
PFR28_03093
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
PFR28_03097
PFR28_03098
PFR28_03099
PFR28_03100
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
PFR28_00165
PFR28_00889
PFR28_03458
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
No genes
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
PFR28_01516
PFR28_03101
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
PFR28_01099
PFR28_02376
PFR28_02925
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
PFR28_01099
PFR28_02376
PFR28_02925
Isocitrate--homoisocitrate dehydrogenase:
D-threo-isocitrate + NAD+→2-oxoglutarate + CO2 + NADH (EC 1.1.1.286; 1.1.1.41)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information