MetaCyc Pathway: superpathway of glycolysis and the Entner-Doudoroff pathway in Pseudomonas sp. RS175

Add experiment(s):


Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+
(EC 1.1.1.49)
PFR28_00573
PFR28_01674
D-glucopyranose[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→D-glucopyranose 6-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.199)
No genes
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+
(EC 3.1.1.31)
PFR28_00574
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate
(EC 5.3.1.9)
PFR28_03724
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+
(EC 2.7.1.11)
No genes
Phosphogluconate dehydratase:
D-gluconate 6-phosphate→2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O
(EC 4.2.1.12)
PFR28_00561
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate
(EC 4.1.2.13)
PFR28_04183
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate
(EC 3.1.3.11)
PFR28_04956
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate
(EC 4.1.2.14; 4.1.2.55)
PFR28_00575
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+
(EC 1.2.1.12)
PFR28_00560
PFR28_01124
PFR28_02335
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate
(EC 5.3.1.1)
PFR28_00085
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP
(EC 2.7.2.3)
PFR28_04186
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
PFR28_04938
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O
(EC 4.2.1.11)
PFR28_00416
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP
(EC 2.7.1.40)
PFR28_03114
PFR28_03455
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate
(EC 2.7.9.2)
PFR28_01038

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information