MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas lactucae CFBP13502

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
GEMAOFIL_00013
GEMAOFIL_00100
GEMAOFIL_01090
GEMAOFIL_01711
GEMAOFIL_01762
GEMAOFIL_01844
GEMAOFIL_01943
GEMAOFIL_02277
GEMAOFIL_02803
GEMAOFIL_02833
GEMAOFIL_03290
GEMAOFIL_03309
GEMAOFIL_03965
GEMAOFIL_04080
GEMAOFIL_04180
GEMAOFIL_04351
GEMAOFIL_04397
GEMAOFIL_04405
GEMAOFIL_04776
GEMAOFIL_05182
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
GEMAOFIL_02938
GEMAOFIL_05035
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
GEMAOFIL_01210
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
GEMAOFIL_01212
GEMAOFIL_02246
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
GEMAOFIL_01211

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information