MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens SBW25

Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

PFLU_RS04475

PFLU_RS08100

PFLU_RS08510

PFLU_RS09125

PFLU_RS10980

PFLU_RS13455

PFLU_RS15480

PFLU_RS16880

PFLU_RS17055

PFLU_RS17810

PFLU_RS19680

PFLU_RS20660

PFLU_RS21080

PFLU_RS21355

PFLU_RS21880

PFLU_RS22640

PFLU_RS22895

PFLU_RS24775

PFLU_RS25195

PFLU_RS29405

PFLU_RS29850

4-hydroxyphenylpyruvate dioxygenase: 3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)

PFLU_RS14610

PFLU_RS26370

Homogentisate 1,2-dioxygenase: homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)

PFLU_RS05085

Maleylacetoacetate isomerase: 4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)

PFLU_RS05095

Fumarylacetoacetase: 4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)

PFLU_RS05090

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information