MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Pseudomonas fluorescens SBW25

Add experiment(s):


Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
PFLU_RS04575
PFLU_RS07475
PFLU_RS11335
PFLU_RS16405
PFLU_RS17035
PFLU_RS18010
PFLU_RS19730
PFLU_RS28695
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
PFLU_RS08090
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
PFLU_RS02490
PFLU_RS04255
PFLU_RS09990
PFLU_RS22735
PFLU_RS23380
PFLU_RS28555
PFLU_RS28655
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
PFLU_RS26190
PFLU_RS26195
PFLU_RS27825

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information