MetaCyc Pathway: superpathway of trimethylamine degradation in Pseudomonas fluorescens SBW25

Add experiment(s):


trimethylamine + NADPH + dioxygen→trimethylamine N-oxide + NADP+ + H2O (EC 1.14.13.148)
PFLU_RS11445
Trimethylamine-oxide aldolase:
trimethylamine N-oxide + H+→dimethylamine + formaldehyde (EC 4.1.2.32)
No genes
dimethylamine + NADPH + dioxygen + H+→formaldehyde + methylamine + NADP+ + H2O (EC 1.14.13.238)
PFLU_RS11460
PFLU_RS11465
Glutamate--methylamine ligase:
methylamine + ATP + L-glutamate→N5-methyl-L-glutamine + ADP + H+ + phosphate (EC 6.3.4.12)
PFLU_RS11405
Methylamine--glutamate N-methyltransferase:
N5-methyl-L-glutamine + L-glutamate + H2O→ammonium + N-methyl-L-glutamate + L-glutamate (EC 2.1.1.21)
PFLU_RS11415
Methylglutamate dehydrogenase:
N-methyl-L-glutamate + an oxidized electron carrier + H2O→formaldehyde + a reduced two electron carrier + L-glutamate (EC 1.5.99.5)
PFLU_RS11385

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information