MetaCyc Pathway: ketogenesis in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
QEN71_RS01125
QEN71_RS02070
QEN71_RS14170
QEN71_RS15980
QEN71_RS18320
QEN71_RS18730
QEN71_RS21880
QEN71_RS22175
QEN71_RS22200
QEN71_RS22970
QEN71_RS27505
Hydroxymethylglutaryl-CoA synthase:
acetoacetyl-CoA + acetyl-CoA + H2O→(S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ (EC 2.3.3.10)
No genes
Hydroxymethylglutaryl-CoA lyase:
(S)-3-hydroxy-3-methylglutaryl-CoA→acetyl-CoA + acetoacetate (EC 4.1.3.4)
QEN71_RS01060
QEN71_RS12120
QEN71_RS12125
QEN71_RS12170
QEN71_RS16990
QEN71_RS30555
QEN71_RS31805
QEN71_RS31810
QEN71_RS39530
QEN71_RS39535
3-hydroxybutyrate dehydrogenase (in reverse):
acetoacetate + NADH + H+→(R)-3-hydroxybutanoate + NAD+ (EC 1.1.1.30)
QEN71_RS05230
QEN71_RS09070
QEN71_RS16050
QEN71_RS17910
QEN71_RS23885
QEN71_RS37110
QEN71_RS38460
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
QEN71_RS09075
QEN71_RS14990

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information